Lacunar infarcts

Lacunar infarcts are small (0.2 to 15 mm in diameter) noncortical infarcts caused by occlusion of a single penetrating branch of a large cerebral artery.

Frontal Lobe Hypometabolism Predicts Cognitive Decline in Patients
http://idealab.ucdavis.edu/

Stroke Pathophysiology
Sid Shah, MD
http://www.uic.edu/

Stroke: An Introduction to Diagnosis
Stephen E. Nadeau, M.D
http://medinfo.ufl.edu

Counting Cavitating Lacunes Underestimates the Burden of Lacunar Infarction
Gillian M. Potter, Fergus N. Doubal, Caroline A. Jackson, Francesca M. Chappell et al
http://depts.washington.edu/

The Blood Supply of the Brain
Relating Vascular and Functional Anatomy
http://www.umassmed.edu/

Dysarthria in acute ischemic stroke Lesion topography, clinicoradiologic correlation,and etiology
P.P. Urban, MD; S. Wicht, MD; G. Vukurevic, PhD; C. Fitzek, MD; S. Fitzek, MD; P. Stoeter, MD;C. Massinger, MD; and H.C. Hopf, MD
http://www.neurosurg.wisc.edu/

An Inverse Association of Cardiovascular Risk and Frontal Glucose Metabolism
Natalie Denburg, PhD: Kuczynski, B., Jagust, W., Chui, H.C., & Reed, B
http://www.healthcare.uiowa.edu/

Diseases of the Nervous System
http://medsci.indiana.edu/

Airway obstruction

Airway obstruction Facts about Childhood Airway Obstruction Injuries
AOI-facts.pdf

Airway Obstruction: It’s not just about stridor
Julie Lynn Fitzgerald, MD
AirwayObstruction.2011.pdf

Choking & Airway Obstruction
SafetyInjuryPrevention/ChokingAirwayObstruction.pdf

An Unusual Cause of Airway Obstruction during General Anesthesia with a Laryngeal Mask Airway
Christopher M. Bernards, M.D
Unusual Cause of Airway Obstruction.pdf

Injury Facts: Airway Obstruction
Assign-1b-Airway-Obstruction-3.pdf


An unexpected functional cause of upper airway obstruction
L. G. Michelsen, A . F. L. Vanderspek
unexpected functional cause .pdf


Airway management and ventilation
Airway management and ventilation.pdf

Upper Airway Obstruction
Upper_Airway_Obstruction_Case.pdf


Airway Management
http://www.siumed.edu/oec/anesthesiology/Anes2.pdf

Foreign Body Airway Obstruction and CPR for an Infant
http://www.jchs.edu/media/147_InfantCheckSheet.pdf
 
Airway Obstruction in Asthma: Does the Response to a Deep Inspiration Matter?
Fredberg, Jeffrey J.
Airway Obstruction in Asthma.pdf


Oscillometric assessment of airway obstruction in a mechanical model of vocal cord dysfunction
Oscillometric assessment of airway obstruction.pdf

Preventing Childhood Airway Obstruction Injuries
http://ukhealthcare.uky.edu/uploadedFiles/AOI-tips.pdf

Multiple system atrophy as a cause of upper airway obstruction
Y. S. Lim1 and N. J. Kennedy
Multiple system atrophy.pdf

Airway obstruction such as with mucus or poor positioning
FactorsthatPromoteApneainthePrematureInfant.pdf

Key Articles for Upper Airway Obstruction
Upper_Airway_Obstruction_Key_Articles.pdf

Cerebellar abnormalities

Cerebellar abnormalities in infants and toddlers with Williams syndrome
Wendy Jones, John Hesselink , Eric Courchesne, Tim Duncan, Kevin Matsuda,Ursula Bellugi
Cerebellar abnormalities in infants.pdf

Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia
I D Wilkinson, M Hadjivassiliou, J M Dickson, L Wallis, R A Grünewald, S C Coley, E Widjaja and P D Griffiths
Cerebellar abnormalities.pdf

Eyeblink conditioning deficits indicate timing and cerebellar abnormalities in schizophrenia
S.M. Brown, P.D. Kieffaber, C.A. Carroll, J.L. Vohs, J.A. Tracy, A. Shekhar, B.F. O’Donnella, J.E. Steinmetza, W.P. Hetricka
Eyeblink conditioning deficits.pdf

Cerebellar Abnormalities in Adolescents with Marijuana Dependence
M. Lopez-Larson, J. Rogowska3, and D. Yurgelun-Todd,
Cerebellar Abnormalities in Adolescents.pdf

Symmetric bilateral caudate, hippocampal, cerebellar, and subcortical white matter MRI abnormalities
Sajan Mahajan, MD, and William G. Schucany, MD
Symmetric bilateral caudate, hippocampal.pdf

Cardiovascular Congenital Deformities

Classic Imaging Signs of Congenital Cardiovascular Abnormalities
Emma C. Ferguson, MD, Rajesh Krishnamurthy, MD, Sandra A. A.Oldham, MD, FACR
Congenital Cardiovascular Abnormalities.pdf

congenital cardiovascular disease
Towson University
CongenitalCardiovascularDisease.pdf


Cyanotic Congenital Heart Disease with Increased Pulmonary Blood Flow
Ronald G. Grifka, MD
Pulmonary Blood Flow.pdf

Congenital Deformities of the Upper Extremity
Gregory G. Gallant, MD, and F. William Bora, Jr, MD
Congenital Deformities of the Upper Extremity.pdf

MPOC: Preparticipation Sports / Cardiovascular Evaluation
Preparticipation Sports/Cardiovascular Evaluation.pdf

Left Basilar Systolic Murmur in Retired Racing Greyhounds
F. Fabrizio, R. Baumwart, M.C. Iazbik, K.M. Meurs, and C.G. Couto
Left Basilar Systolic Murmur.pdf

Heart Disease in The Young
Charles S. Kleinman, M.D.
Heart Disease in The Young.pdf

Impact of Co-Occurring Birth Defects on the Timing of Newborn Hearing Screening and Diagnosis
Derek A. Chapman, Caroline C. Stampfel, Joann N. Bodurtha, Kelley M. Dodson, Arti Pandya, Kathleen B. Lynch and Russell S. Kirby
occurring_birth_defects_and_newborn_hearing_screening_-_dx.pdf

Development of the Cardiovascular System
Thomas A. Marino, Ph.D
Development of the Cardiovascular System.pdf

The Emerging Recognition of School and Behavior Problems in Children with Congenital Heart Defects (CHD)
Long-term-effects-chd.pdf

Assessment and Management of Patients with Diabetes Mellitus

Diabetic Foot Ulcers: Pathogenesis and Management
ROBERT G. FRYKBERG, D.P.M., M.P.H., Des Moines University, Des Moines, Iowa
http://geriatrics.uthscsa.edu/tools/DiabeticFootUlcers-Frykberg.pdf

Michigan Quality Improvement Consortium Guidelines Management of Diabetes Mellitus
Management of Diabetes Mellitus.pdf

Assessment and Management of Patients With Diabetes Mellitus
Assessment and Management of Patients.pdf

Official reprint from UpToDate® Perioperative management of diabetes mellitus
DiabetesManagementinSurgicalPatients.pdf

The Standard of Care for Evaluation and Treatment of Diabetic Foot Ulcers A CME/CE Monograph
http://www.barry.edu/cme/pdf/journals/diabetic.PDF

The Relationship Between Diabetes and Periodontal Disease
Debora C. Matthews, DDS, Dip Perio, MSc
Relationship Between Diabetes and Periodontal Disease.pdf

Adapting Your Practice: Treatment and Recommendations for Homeless Patients with Diabetes Mellitus
Treatment and Recommendations for Homeless Patients with Diabetes Mellitus.pdf

Clinical Procedure - Clinical Manual – Nursing Practice Manual
http://nursing.uchc.edu/nursing_standardsClinical Procedure - Clinical Manual.pdf

Diabetic nephropathy: Do all patients with Diabetes Mellitus benefit from an ACE-I or ARB?
Carrie Rogers, Pharm.D
http://www.utexas.edu/pharmacy/divisions/pharmaco/rounds/rogers.pdf

Perioperative management of ambulatory surgical patients with diabetes mellitus
Mary Ann Vann
http://ether.stanford.edu/asc/documents/dm2.pdf

Patient-assessed health outcome measures for diabetes: a structured review
A. M. Garratt, L. Schmidt and R. Fitzpatrick
http://www.atsu.edu/research/pdfs/Diabetes_Outcomes.pdf

Current Antihyperglycemic Treatment Guidelines and Atgorithms for Patients with Type 2 Diabetes Mellitus
Lawrence Blonde, MD, FACP, FACE
Antihyperglycemic Treatment Guidelines.pdf

Peptic Ulcer PDFs and recent 50 free scholarly articles

Stress and Peptic Ulcer Disease
Susan Levenstein, MD, Sigurd Ackerman, MD, Janice K. Kiecolt-Glaser, PhD, André Dubois, MD
Stress and Peptic Ulcer Disease.pdf

Peptic Ulcer Disease
Thomas S. Foster, Pharm.D.
Peptic Ulcer Disease.pdf

Perforated Gastric Ulcers - A Plea for Management by Simple Closure
William W. Turner, Jr, MD; William M. Thompson, Jr, MD;Erwin R. Thal, MD
Perforated Gastric Ulcers.pdf

Peptic Ulcer Disease - Guidelines for Clinical Care
A. Mark Fendrick, M.D.,Randall T. Forsch, M.D., R. Van Harrison, Ph.D., James M. Scheiman,M.D
Peptic Ulcer Disease - Guidelines for Clinical Care.pdf

Helicobacter pylori in Peptic Ulcer: Have Koch’s Postulates Been Fulfilled?
Barry J. Marshall
Helicobacter pylori in Peptic Ulcer.PDF

Treatment of Peptic Ulcer Disease (2011)
David Guay, Pharm.D. F.C.P,F.C.C.P,F.A.S.C.P
Peptic Ulcer Disease.pdf

Do corticosteroids cause peptic ulcers?
Todd May, MD
Corticosteroids.pdf

Peptic Ulcers
Peptic_ulcers.pdf

Pharmacokinetics, Pharmacodynamics

Pharmacodynamics: Tolerance & Dependence
http://psych.fullerton.edu/mwhite/475pdf/475Pharmacodynamics-ToleranceandDependence.pdf

The Pharmacokinetics and Pharmacodynamics of Thiopental as Used in Lethal Injection
Mark Dershwitz, M.D., Ph.D.  & Thomas K. Henthorn, M.D.
http://www.law.berkeley.edu/clinics/dpclinic/LethalInjection/LI/documents/articles/journal/dershwitz.pdf

Pharmacokinetics, Pharmacodynamics and Rational Opioid Selection
Steven L. Shafer, M. D.,* John Fl. Varvel, M.D.T
http://etherweb.bwh.harvard.edu/education/resources/ambulatory_anesthesia/Pharmacokinetics_Opioids.pdf

Pharmacokinetics and pharmacodynamics of safinamide, a neuroprotectant with antiparkinsonian and anticonvulsant activity
Antonio Marzoa, , Lorenzo Dal Boa, Nunzia Ceppi Montia, Fabrizio Crivellia, Shevqet Ismailia, Carla Cacciab, Carlo Cattaneob, Ruggero G. Fariello
http://course1.winona.edu/bsvingen/chem402/Pharm%20Data.pdf

Modeling Pharmacokinetics and Pharmacodynamics on a Mobile Device to Help Caffeine Users
Frank E. Ritter and Kuo-Chuan (Martin) Yeh
http://acs.ist.psu.edu/papers/ritterY11.pdf

Pharmacokinetics and Pharmacodynamics
Dr. Palmer Taylor
http://pharmacology.ucsd.edu/graduate/courseinfo/Taylor-Pharmacokinetics%20and%20Pharmacodynamics.pdf

Pharmacodynamics of Antidepressants Mood Stabilizing Agents Anxiolytics Sedative-Hypnotics
Yogesh Dwivedi, Ph.D.
http://www.uic.edu/classes/pcol/pcol331/dentalpharmhandouts2006/lecture48.pdf

Pharmacodynamics of Antipsychotics Anxiolytics Sedative-Hypnotics
Yogesh Dwivedi, Ph.D.
Pharmacodynamics of Antipsychotics Anxiolytics Sedative-Hypnotics.pdf

The Pharmacodynamics of Antibiotic Treatment
Mudassar Imran and Hal Smith
The Pharmacodynamics of Antibiotic Treatment.pdf

The Pharmacokinetics and Pharmacodynamics Of CNS-Acting Agents
By Mohamed A. Kamal
The Pharmacokinetics and Pharmacodynamics Of CNS-Acting Agents.pdf

Pharmacodynamics of Oral Ganciclovir and Valganciclovir in Solid Organ Transplant Recipients
Hugh Wiltshire,Carlos V. Paya, Mark D. Pescovitz, Atul Humar, Edward Dominguez, Kenneth Washburn, Emily Blumberg, Barbara Alexander, Richard Freeman, Nigel Heaton, Klaas P. Zuideveld
Pharm-oral.pdf

“Pharmacokinetics” – what the body does to the drug
“Pharmacodynamics” – what the drug does to the body
Pharmacodynamics-Dosage and DrugEffects.pdf

Pharmacodynamics
PharmacoDynamics.pdf

Pharmacodynamics of antimicrobial drugs
Matthew E. Levison, MD
Pharmacodynamics of antimicrobial drugs.pdf

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: Role of circulating active metabolites
Pharmacokinetics and pharmacodynamics of oral oxycodone.pdf

Between Dose and Response: Pharmacokinetics, Pharmacodynamics, and Statistics
Marie Davidian
Between Dose and Response.pdf

Polymyositis and Dermatomyositis

Polymyositis and dermatomyositis
Marinos C Dalakas, Reinhard Hohlfeld
https://uthsc.edu/Myositis.pdf

Polymyositis and dermatomyositis
http://medicine.ucsf.edu/dermatomyositis.pdf

Dermatomyositis and The Lung
http://medicine.ucsf.edu/dermatomyositis.pdf

Clinical and Biochemical Characteristics of Autoantibody Systems in Polymyositis and Dermatomyositis
By Edward J. Fudman and Thomas J. Schnitzer
http://deepblue.lib.umich.edu/bitstream.pdf

Dermatomyositis without Creatine Kinase Elevation A Poor Prognostic Sign
EDWARD J. FUDMAN, M.D., THOMAS J. SCHNITZER, M.D., Ph.D
http://deepblue.lib.umich.edu/bitstream/.pdf

Dermatomyositis and ILD
http://www.eric.vcu.edu/masters.pdf

Scleroderma and Myositis
Seth Mark Berney, MD
http://www.sh.lsuhsc.edu/Myositis.pdf

Immune-mediated neuromuscular disorders
http://www.case.edu/med/CTN.pdf

Myositis
http://www.medicine.iupui.edu/Myositis_brochure.pdf

Dermatomyositis – Association with malignancy and patient evaluation
http://www.hopkinscme.net/.pdf

Prenatal Diagnosis

Prenatal Diagnosis of Vascular Anomalies
Vascular Anomalies.pdf

Prenatal Diagnosis Screening Questionnaire
Prenatal-diag-screening-quest.pdf

Prenatal Diagnosis Objectives
Prenatal Diagnosis Objectives.pdf

Sensitivity of Noninvasive Prenatal Detection of Fetal Aneuploidy from Maternal Plasma Using Shotgun Sequencing Is Limited Only by Counting Statistics
H. Christina Fan, Stephen R. Quake
Noninvasive Prenatal Detection.pdf

Brief Clinical Report: Prenatal Diagnosis of Congenital Diaphragmatic Hernia Not Amenable to Prenatal or Neonatal Repair: Brachmann-de Lange Syndrome
Russel D. Jelsema, Nelson B. Isada, Nadya J. Kazzi, Kate Sargent, Michael R. Harrison, Mark P. Johnson, and Mark I. Evans
Prenatal Diagnosis.pdf

Non-Invasive Prenatal Diagnosis (NIPD): Bioethical reflections on the future of prenatal genetic testing
Vardit Ravitsky, PhD
NIPD_UPenn_Feb2012.pdf

Prenatal  Diagnosis  /  Ultrasound  Service Questionnaire
Ultrasound-mfm-2.pdf

Non-invasive prenatal diagnosis of Down’s syndrome
M A Hultén, R W Old
http://www.genetics.iastate.edu/bell4.pdf

Why I Haven't Changed My Mind about Prenatal Diagnosis Reflections and Refinements
Prenatal Diagnosis Reflections.pdf

Down Syndrome: Offer of Prenatal Diagnosis
Down Syndrome.pdf

Prenatal Diagnosis
Diana W. Bianchi, M.D.
http://ocw.tufts.edu/Prenatal Diagnosis.pdf

Prenatal Diagnosis and The Selection Of Children
Jeffrey R. Botkin
Prenatal Diagnosis and The Selection Of Children.pdf

Bariatric surgery - lecture notes and 50 scholarly articles

Clinical Review - Gastrointestinal and Nutritional Complications After Bariatric Surgery
G. Anton Decker, M.B.B.Ch., M.R.C.P., James M. Swain, M.D., Michael D. Crowell, Ph.D. and James S. Scolapio, M.D
http://gidiv.ucsf.edu/course/things/ajgcomp.pdf

Bariatric Surgery Pre-Op Instructions
J. R. Salameh, M.D., FACS
Bariatric Surgery Pre-Op Instructions.pdf

Physical Activity & Exercise Strategies For Bariatric Surgery Patients
http://www.uchospitals.edu/pdf/uch_015743.pdf

Bariatric surgery What new patients need to know about weight reduction surgery
What new patients need to know about BARIATRIC-SURGERY.pdf

Controversies in Bariatric Surgery
Bariatricbrochure.pdf

Weight Loss Surgery Preoperative Workbook
Sayeed Ikramuddin, MD etal
Patient Workbook.pdf

Bariatric Surgery Guide
Roux-en-y gastric bypass edition
Bariatric Surgery Guide.pdf

Weight Loss Surgery - Pre-Clinic Conference
Jennifer Kinley, MD
WLS-Presenation.pdf

What is the Longitudinal Assessment of Bariatric Surgery (LABS)?
LABSFactSheet.pdf

Psychiatric Disorders Among Bariatric Surgery Candidates:
Relationship to Obesity and Functional Health Status
Melissa A. Kalarchian, Ph.D etal
http://www.prefer.pitt.eduPsychiatric Disorders Among BS Candidates.pdf

Role of Bariatric Surgery in Diabetes
James R. Wallace MD PhD,
Wallacediabetes10.pdf

Bariatric Surgery Program Questionnaire
Questionnaire.pdf

Gastrointestinal and Nutritional Complications of Bariatric Surgery
Matt Cave, MD, Luis S. Marsano, MD
Bariatric Surgery.pdf

The Evolution of Severe Steatosis After Bariatric Surgery Is Related to Insulin Resistance
Philippe Mathurin, Florent Gonzalez, Olivier Kerdraon, Emmanuelle Leteurtre etal
Steatosisafterbariatricsurgery.pdf

Clinical Pearls for Emergency Care ofthe Bariatric Surgery Patient
Clinical Pearls for Emergency Care.pdf

Electrophysiology

Anatomy and Electrophysiology of the Heart
anatomyelectrophysiologyheart.pdf

Cellular Electrophysiology
electro-cell.pdf

Electrophysiology and AxoClamp Tutorial
Daniel Wagenaar
ephys-axo.pdf

Indications for Electrophysiological Testing
Samuel C. Dudley, Jr., M.D., Ph.D.
EPtesting.pdf

Synaptic Electrophysiology of the Drosophila Neuromuscular Junction
NEURO_12.pdf

Selective attention: Electrophysiological and neuromagnetic studies
Joseph B. Hopfinger, Steven J. Luck, & Steven A. Hillyard
Hopfinger_04.pdf

EPS: Electrophysiology Studies
pfrc99-000005.pdf
An Electrophysiologist’s Introduction to Matlab — with Examples and Exercises
Daniel A. Wagenaar
matlab4ephys.pdf

Alcoholism and Human Electrophysiology
Bernice Porjesz, Ph.D., and Henri Begleiter, Ph.D
Alcoholism and Human Electrophysiology.pdf

Electrophysiological Methods
Leon Avery, David Raizen and Shawn Lockeryt
Ephys_methods/paper.pdf

Electrophysiology Notes
Jeremy Payne
Electrophys.pdf

Electrophysiology of The Neuron An Interactive Tutorial
John Huguenard, David A.Mccormick
Neuron An Interactive.pdf

Transverse Myelitis PDFs and free access published articles

Transverse myelitis is a neurological disorder caused by inflammation across both sides of one level, or segment, of the spinal cord. The segment of the spinal cord at which the damage occurs determines which parts of the body are affected.

Transverse myelitis
http://eradiology.bidmc.harvard.edu/LearningLab/central/Kaufman.pdf

Recurrent Myelitis Associated With Hepatitis C Infection
www.bcm.edu/neurology/pdf/poster_other_RecurrentMyelitis.pdf

Neuro MRI Ordering Guide
MRI_Ordering_Guide2_1_.pdf

General Information Regarding MS
General_information_regarding_ms.pdf

NMO-IgG predicts the outcome of recurrent optic neuritis
NMO-IgG Rose-Innes_article1.pdf

Aquaporin-4 Antibodies in Neuromyelitis Optica and Longitudinally Extensive Transverse Myelitis
Patrick Waters, PhD; Sven Jarius, MD; Edward Littleton, MBBS, DPhil; Maria Isabel Leite, MD etal
Aquaporin-4 Antibodies in Neuromyelitis.pdf

Transverse myelitis - Case study
Transverse myelitis.pdf

Diagnosis of Transverse Myelitis: An Evaluation of the factors leading to Spinal Dysfunction
Including a Review of one patients’ experience
Diagnosis of Transverse Myelitis.pdf

Imaging Sciences Interesting Cases
Jacinto Camarena III, MD
IS_Case12.pdf

Prothrombin Complex Concentrate

Safety of prothrombin complex concentrates
www.medicine.wisc.edu/~williams/PCC_meta.pdf

Reversal of Rivaroxaban and Dabigatran by Complex Concentrate
www.medicine.wisc.edu/~williams/PCC_Riva.pdf

Dabigatran etexilate – a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
Joanne van Ryn; Joachim Stangier; Sebastian Haertter; Karl-Heinz Liesenfeld; Wolfgang Wienen; Martin Feuring; Andreas Clemens
Dabigatran_review_2010.pdf

Prothrombin Complex Concentrates: Are They Effective for
Rapid Reversal of Anticoagulation in the ED Setting?
Presenters: Jill Aston M.D. and Roderick W. Fontenette M.D
Synopsis.pdf

Anticoagulant Management Program and Guidelines
Ronald Reagan UCLA Medical Center
Guidelines_anticoagulation.pdf

Laboratory Monitoring of Direct Thrombin Inhibitors
David Williams, M.D., Ph.D., Roger S. Riley, M.D., Ph.D., Ann Tidwell, M.T. (ASCP) SH
DTI.pdf

Treating CNS Hemorrhage in the Anticoagulated Patient
Andrew W. Asimos, MD
CNS Hemorrhage in the Anticoagulated .pdf

Policies and Procedures for The Anticoagulation Case Management Service
At The University of Iowa Hospitals and Clinics
ACMSpoliciesprocedures.pdf

Hemostasis and Coagulation
Hemostasis and Coagulation.pdf

Anticoagulants: The Quick Guide to Use and Reversal
Thomas G. DeLoughery, MD, FACP
Anticoagulants: The Quick Guide to Use and Reversal.pdf
Prothrombin Complex Concentrate Ppts

Pituitary Disorders

Pregnancy and pituitary disorders
Z Karatra. F Tanrivcrdi. K Unluhisearci and F Koleslimur
http://pathology2.jhu.edu/

Pituitary Disorders: Advances in Diagnosis and Management
Grand Hyatt, San Francisco
http://endocrine.medicine.ucsf.edu/

Anterior Pituitary Disorders
Joseph N. Fisher, M.D
http://www.uthsc.edu/

Case-Based Update on Pituitary Disorders
Marriott Atlanta Buckhead
http://www.med.emory.edu/

Disorders of Water and Salt Metabolism Associated with Pituitary Disease
Jennifer A. Loh, MD, Joseph G. Verbalis, MD
http://www.medicine.nevada.edu/

Pituitary Gland Anterior Pituitary (adenohypophysis)
http://www.austincc.edu/

Assessment and Management of Patients With Endocrine Disorder
http://www.ccri.edu

What to Expect After Pituitary Surgery
http://ccpd.ucsf.edu

Hypothalamic-pituitary-adrenal Axis and Bipolar Disorder
C. Daban, PhDa, E. Vieta, MD, PhDa, P. Mackin, MB, BS, PhD, MRCPsych,A.H. Young, MB, ChB, MPhil, PhD, RCPsych
http://www.sci.sdsu.edu/

Pituitary Patient Education
http://www.ucdenver.edu

Effect of Comorbid Anxiety Disorders on the Hypothalamic-Pituitary-Adrenal Axis Response to a Social Stressor in Major Depression
Elizabeth A. Young, James L. Abelson, and Oliver G. Cameron
Youngcomorbidity.pdf

Lectures covering the Model of the Clinical Practice of Emergency Medicine
http://www.med.wright.edu
Pituitary Disorders in Ppt format

Mycetoma

Mycetoma: Mycetoma is a chronic subcutaneous infection caused by actinomycetes or fungi. This infection results in a granulomatous inflammatory response in the deep dermis and subcutaneous tissue.

A Ward in the Mycetoma
Mycetoma guidelines-2.pdf

Subcutaneous Mycoses
SubcutaneousMycoses.pdf

The characteristics of Aspergillus fumigatus mycetoma development: is this a biofilm?
Aspergillus fumigatus mycetoma.pdf

Subcutaneous Fungi Study Questions - KEY
SFungi.pdf

Eumycetoma: A Clinical Overview
Presenter: Michael Stephen Bolton
Eumycetoma.pdf

The Fifth International Conference on Mycetoma
5th-con/conference recommondations.pdf

Pulmonary Aspergillosis
Pulmonary Aspergillosis.pdf

Subcutaneous Fungi: Clinical Laboratory Science Program
Carol Larson MSEd, MT(ASCP)
Subcutaneous Fungi.pdf
View Ppts here

Unstable Angina NonST-Elevation Myocardial Infarction

2011 ACCF/AHA Focused Update of the Guidelines for the Management of Patients With Unstable Angina/NonST-Elevation Myocardial Infarction
Unstable Angina NonST-Elevation Myocardial Infarction.pdf

Validation of Electrocardiographic Criteria for Predicting the Culprit Artery in
Patients with Acute Myocardial Infarction
NHJJ van der Putten, PR Rijnbeek, WA Dijk, G van Herpen, AC Maan, JA Lipton, JA Kors
http://cinc.mit.edu/current/preprints/174.pdf

ACC/AHA Guidelines for the Management of Patients With Unstable Angina and Non–ST-Segment
Elevation Myocardial Infarction: Implications for Emergency Department Practice
Charles V. Pollack, Jr, MA, MD, Eugene Braunwald, MD
ACC/AHA Guidelines.PDF

Pharmacological Treatment of Unstable Angina (UA) and Non St-Segment Elevation Myocardial Infarction (NSTEMI)
Pharmacological Treatment of Unstable Angina.pdf

TIMI Risk Score for UA/NSTEMI
TIMI Risk Score for UA/NSTEMI

Treatment of ACS - UA/NSTEMI Initial Therapy
Michael P. Gulseth, Pharm. D., BCPS
Lectures/ACS2.pdf

Postoperative Myocardial Infarction: Diagnosis and Management
Todd M. Brown, MD, MSPH
Geriatrics Post-Surgical MI.pdf

UCLA Chest Pain and ACS Patient Management Guideline
UCLA.pdf

Therapeutic Hypothermia and Emergency Cardiopulmonary Bypass after Cardiac Arrest: Role of the Cardiac Cath Lab
ECPBcathcopy.pdf

Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction:
Initial Evaluation and Management, and Hospital Care
STEPHEN D. WIVIOTT, M.D., and EUGENE BRAUNWALD, M.D
Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction.pdf

Excellence in Care: Protocols for the Management of Cardiac Conditions
Pam Bayles RN, BSN
Excellence in Care: Protocols.pdf
Ppts on the subject here

Temporomandibular Joint Derangement

Occlusal Splints for Temporomandibular Disorders (TMD), Bruxism, or Clenching
http://medweb.mit.edu/pdf/occlusalsplints.pdf

Medical Progress - Temporomandibular Disorders
Steven J. Scrivani, D.D.S., D.Med.Sc., David A. Keith, B.D.S., D.M.D., and Leonard B. Kaban, D.M.D., M.D
Temporomandibular Disorders.pdf

EVIDENCE-BASED ORTHODONTICS - Occlusal adjustment for treating and preventing temporomandibular disorders
Greg J. Huang, DMD, MSD, MPH
Occlusal adjustment for treating.pdf

Temporomandibular iontophoretic A Double-Blind Randomized Clinical Trial
Temporomandibular iontophoretic.pdf

Symposium on What is Working in Treating theTemporomandibular Joint
TreatingTMJ.pdf

Temporomandibular Disorders (TMD)
Sven E Widmalm DDS, Dr. Odont.
tm_disorders.pdf

MRI Findings of Rheumatoid Arthritis in the Temporomandibular Joint
Peter H. Takeyama etal
MRI Findings of Rheumatoid Arthritis.pdf

Temporomandibular Joint Pain and Dysfunction
Kathleen Herb, DMD, MD, Sung Cho, DMD, and Marlind Alan Stiles, DMD
Joint Pain and Dysfunction.pdf
PPTs here

Diagnostic Testing PDF Lecture Notes

Allergy Diagnostic Testing: An Updated Practice Parameter
I. Leonard Bernstein, MD; James T. Li, MD, PhD; David I. Bernstein, MD; Robert Hamilton, PhD, DABMLI; Sheldon L. Spector, MD; Ricardo Tan, MD; Scott Sicherer, MD; David B. K. Golden, MD; David A. Khan, MD; Richard A. Nicklas, MD; Jay M. Portnoy, MD; Joann Blessing-Moore, MD; Linda Cox, MD; David M. Lang, MD; John Oppenheimer, MD; Christopher C. Randolph, MD; Diane E. Schuller, MD; Stephen A. Tilles, MD; Dana V. Wallace, MD; Estelle Levetin, PhD; and Richard Weber, MD
http://pollen.utulsa.edu/Practice%20Parameters.pdf

Low Sensitivity of Rapid Diagnostic Test for Influenza
Timothy M. Uyeki, Ramakrishna Prasad, Charles Vukotich, Samuel Stebbins, Charles R. Rinaldo, Yu-hui Ferng, Stephen S. Morse, Elaine L. Larson, Allison E. Aiello, Brian Davis and Arnold S. Monto
www.pipp.pitt.edu/pdf/Uyeki-accepted.pdf

Some Issues in Resolution of Diagnostic Tests using an Imperfect Gold Standard Technical Report
Douglas M. Hawkins etal
http://www.stat.umn.edu/hawkins/Resolving_V7_fix.pdf

Evaluation of Diagnostic Tests
Introduction to Clinical Research: A Two-week Intensive Course
Milo A. Puhan, MD, PhD
Evaluation of Diagnostic Tests.pdf

A Systematic Review of Diagnostic Tests for Small Intestinal Bacterial Overgrowth
Reza Khoshini, Sun-Chuan Dai, Sheila Lezcano, Mark Pinientel
www.gastro.ucsd.edu/fellowship/Documents/SmallBowel2.pdf

Diagnostic Test for HIV
Dr. Pearl Fernandes
http://www.meredith.edu/kenya/sum_pf_diagnostic_test_HIV.pdf

Evaluation of Diagnostic and Screening Tests: Validity and Reliability
Sukon Kanchanaraksa, PhD, Johns Hopkins University
http://ocw.jhsph.edu/courses/fundepi/PDFs/Lecture11.pdf

"Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice", this worksheet can serve as an aid to the critical appraisal of an article about interpreting diagnostic test results.
Diagnostic%20Test.pdf

Diagnostic Testing and Care Of New SMA Patients
https://smaregistry.iu.edu/Links/Downloads/SMA_SOC_EN.pdf

Comparing diagnostic tests: a simple graphic using likelihood ratios
Brad J. Biggerstaff
http://www.stat.colostate.edu/~bradb/papers/lrgraphfinal.pdf

The diagnostic odds ratio: a single indicator of test performance
Afina S. Glas, Jeroen G. Lijmer, Martin H. Prins,Gouke J. Bonsel, Patrick M.M. Bossuyt
The diagnostic odds ratio.pdf

Handbook of Diagnostic Virology Testing
Offered by UW Medicine
Clinical/Guides/virotext.pdf

Diagnostic Tests Study Guide
California State University, Sacramento
DiagnosticTestStudyGuide.pdf

Liver Diagnostic Tests
Steven K. Herrine, MD
Liver Diagnostic Tests.pdf
Diagnostic Tests PPts Here

Anisocoria lecture notes

Anisocoria, or unequal pupil sizes, is a common condition. The varied causes have implications ranging from life threatening to completely benign.

An Infant With New Onset Anisocoria in the Preoperative Area
Zoel Quiñónez, M.D. and Niroop Ravula, M.D., F.R.C.A.
Anisocoria in the Preoperative Area.pdf

Functional Difficulties Resulting from Traumatic Anisocoria
ELI PELI
Peli_Am.J.Opt.and.Physio.Optics_1984.pdf

Neuro-ophthalmologic Examination of the Neurosurgical Patients
Amgad Hanna, MD and Peter Savino, MD
N-ophthoFinal2.pdf

Pupillary Examination: Do I Really Need to Look?
Wanda Pfeifer, OC(c), COMT, Amanda Denker, BA
Pupillary Examination.pdf

Neuro-Ophthalmic Examination Techniques
Denise Goodwin, OD, FAAO
Neuro-OphthalmicExaminationTechniques.pdf

The Pupil
http://www.nyee.edu/pdf/okap-banik-the-pupil.pdf

Portable Pupillography of the Swinging Flashlight Test to Detect Afferent Pupillary Defects
Nicholas J. Volpe, MD, Elizabeth S. Plotkin, MD, Maureen G. Maguire, PhD, Ravi Hariprasad, BS, Steven L. Galetta, MD
PortablePupillographyoftheSwinging.pdf

Special Systems Pharmacology
Special Systems Pharmacology.pdf

Vision-Screening Evaluation Sheet
Vision-Screening Evaluation Sheet.pdf
View PPts here

Myasthenia Gravis

Myasthenia Gravis:Myasthenia gravis is a neuromuscular disorder. Neuromuscular disorders involve the muscles and the nerves that control them.

New England Medical Center Grand Rounds - Myasthenia Gravis
Myasthenia Gravis.pdf

Ocular motor dysfunction and ptosis in ocular myasthenia gravis: effects of treatment
M J Kupersmith and G Ying
ocular myasthenia gravis.pdf

Rituximab in the Management of Refractory Myasthenia Gravis
NAZLEE ZEBARDAST, MS, HUNED S. PATWA, MD, STEVEN P. NOVELLA, MD, and JONATHAN M. GOLDSTEIN, MD
Management of Refractory Myasthenia Gravis.pdf

Juvenile myasthenia gravis: an unusual presentation
Phillips H. Winter and Charles F. Koopmann Jr.
Juvenile myasthenia gravis.pdf

Myasthenia. Gravis and Myasthenic Syndromes
Mark B. Bromberg
Myasthenic Syndromes.pdf

Myasthenia gravis: clinical, immunological and therapeutic advances
Myasthenia gravis.pdf

Evidence report: The medical treatment of ocular myasthenia (an evidence-based review)
Report of the Quality Standards Subcommittee of the American Academy of Neurology
M. Benatar, MBChB, MS, DPhil and H.J. Kaminski, MD, FAAN
Evidence report.pdf

Myasthenia gravis - Brief Outline
Myasthenia gravis - Brief Outline.pdf

Myasthenia gravis Getting the Message Across
WellAware-summerrevision.pdf

Myasthenia gravis
Myasthenia_gravis.pdf

Respiratory pharmacology PDF

Respiratory Pharmacology
Dr. Mike White
Respiratory Pharmacology.pdf

Respiratory Pharmacology
http://wids.matcmadison.edu/10515173.pdf

Respiratory Therapist - Academic Planner
Respiratory Therapist.pdf

Respiratory Care Therapist
http://www.occc.edu/CourseCatalog/RCT-AAS.pdf

Respiratory Therapy
Respiratory Therapy.pdf

Applied Science in Respiratory Therapy
RespiratoryTherapy.pdf

Advanced Pharmacotherapeutics
Advanced Pharmacotherapeutics.pdf

Advanced Respiratory Pharmacology
Advanced Respiratory Pharmacology.pdf

Cigarette Smoking Addiction Treatment

Tobacco Addiction
Tobaccorrs_v16_0.pdf

The influence of personality and affect on nicotine dependence among male college students
Dennis E. . McChargue, Lee M. Cohen, Jessica Werth Cook
Mcchargue04.pdf

Validation of a Cigarette Purchase Task
Cigarette Purchase

Differentiating Young Adult Social Smokers on Psychological Constructs
Stacy M. Saunders
Differentiating Young Adult Social Smokers

Fagerström Nicotine Dependence Scale
Nicdependence.pdf

A multiple motives approach to tobacco dependence:
Megan E. Piper, M.A., Thomas M. Piasecki, Ph.D., E. Belle Federman, Sc.D., Daniel M. Bolt, Ph.D., Stevens S. Smith, Ph.D., Michael C. Fiore, M.D., M.P.H., and Timothy B., Baker, Ph.D
WISDMManuscript.pdf

Fagerström Test for Nicotine Dependence (Adults)
QUESTIONNAIRES.pdf

How to use an Extended Tobacco Cessation Intervention Form
Extended_tcforms.pdf

Nicotine Dependence Syndrome Scale (NDSS)
http://www.psychology.pitt.edu/research/publications/NDSS.pdf

Smokeless Tobacco Characteristics
Tobacco Characteristics

Nicotine Addiction and Its Assessment
Kari Olov Fagerstrom. Ph.D., Todd F. Heatherton. Ph.D., Lynn T. Kozlowski. Ph.D.
http://www.dartmouth.edu/~thlab/pubs/90_Fagerstrom_etal_ENTJ.pdf

Ppts on Cigarette Smoking

Diabetes Drug Improves Glucose Control Without Increasing Risk of Hypoglycemia

Diabetes Drug Improves Glucose Control Without Increasing Risk of Hypoglycemia

Too high? Too low? Only about half of those with type 2 diabetes have their blood sugar levels on target, but a new drug shows promise in managing glucose levels.  TAK-875 works by boosting the release of insulin from pancreatic B cells, but only when diabetics need it most – such as when glucose and fatty acids rise in the blood after a meal.

TAK-875, a new treatment for type 2 diabetes, improves blood sugar control and is equally effective as glimepiride, but has a significantly lower risk of creating a dangerous drop in blood sugar, called hypoglycemia, according to a new study.


Takeda Pharmaceutical has reported the positive results from its Phase 2 trial of TAK-875 in patients with type 2 diabetes.

TAK-875 is a selective agonist of GPR40, one of the GPCRs that are expressed in pancreatic islet cells.

The Phase 2 trial is a randomized double-blind placebo- and active (glimepiride) comparator-controlled multicenter study, intended to evaluate once-daily treatment with five different doses of TAK-875 (6.25 mg, 25 mg, 50 mg, 100 mg, and 200 mg) and glimepiride (2 mg -4 mg), over 12 weeks.

The study showed that at doses ranging from 6.25 to 200 mg a day, the drug has met its primary endpoint of significantly lowering HbA1c (blood glucose) levels.

The primary objective of the study is the change from baseline in HbA1c levels at week 12, while the secondary endpoints included fasting blood glucose, area under the curve (AUC) for glucose and insulin during an oral glucose tolerance test (OGTT), and body weight.

Takeda Development therapeutic area head Thomas Strack said because of its observed ability to potently stimulate insulin secretion and improve glycemic control with less or no hypoglycemia, these data further support TAK-875 as a potential therapy for the treatment of type 2 diabetes.

TAK-875 is the first GPR40 agonist to reach late-stage Phase 3 clinical development, the company said.
The results of the phase 2 randomized trial were published in The Lancet.


Read full text
http://dx.doi.org/10.1016/S0140-6736(11)61879-5

Lactate Dehydrogenase - LDH Lecture notes

Profiles and prognostic values of serum LDH isoenzymes in patients with haematopoietic malignancies
Fadela BOUAFIA, M.D., Jocelyne DRAI, Ph.D., Jacques BIENVENU, Ph.D., Catherine THIEBLEMONT, M.D., Daniel ESPINOUSE, M.D., Gilles SALLES, M.D., Ph.D., Bertrand COIFFIER, M.D.
http://www.uta.edu/faculty/sawasthi/Enzymology-4351-5324/Class%20Syllabus%20Enzymology/LDHisoenzymesPredictCancerSurvival.pdf

Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells
Carlotta Granchi etal
http://www.scs.illinois.edu/~phgroup/pdfs/ref80_JMedChem_Hergenrother_PDFReprint.pdf

Affinity Chromatography for the Isolation of LDH
http://courses.chem.indiana.edu/s117/documents/Ch5AffinityChromatography.pdf

LDH Isoenzymes By Urea Inhibition And Substrate (Lactate) Modification: A Clinical Evaluation
John G. Batsakis, M.D. and Russell O. Briere, M.D.
LDH Isoenzymes.pdf

Lactate Dehydrogenase-Catalyzed Regeneration of NAD from NADH for Use in Enzyme-Catalyzed Synthesis
H. Kr,trH CsENnulr AND Geoncs M. WSTTESTDES
LDH Regeneration.pdf

Affinity Purification of Lactate Dehydrogenase
Labs/Affinity_Purification_of_LDH.pdf

Lactate Dehydrogenase Isozymes in Tilapiine Fishes (Cichlidae): Tissue Expression and Genetic Variability Patterns
Sherif H. EL-Alfy, Mohamed B. Abdelmordy, Mohamed S. Salama
LDH Isozymes in Tilapiine .pdf