Thursday, February 23, 2012

Borrelia burgdorferi Lyme Disease lecture notes and 50 published articles

Borrelia burgdorferi is a spirochete which is the causative agent of Lyme disease, the most common tick-borne disease in the United States.

Borrelia burgdorferi

Genomic sequence of a Lyme disease spirochaete

Evolution of Northeastern and Midwestern Borrelia burgdorferi

Contrasts in Tick Innate Immune Responses to Borrelia burgdorferi Challenge:
Immunotolerance in Ixodes scapularis Versus Immunocompetence in Dermacentor variabilis (Acari: Ixodidae)

TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferi

Occurrence of Ixodes scapularis and Borrelia burgdorferi among Small Mammal Populations in East Central Illinois

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells
by Woo-Yong Lee1, Tara J Moriarty, Connie H Y Wong, Hong Zhou, Robert M Strieter, Nico van Rooijen, George Chaconas & Paul Kubes

Transfusion Related Transmission of Borrelia Burgdorferi

Lyme Disease

Spotted Fever Group Rickettsiae or Borrelia burgdorferi in Ixodes cookei (Ixodidae) in Connecticut

The Elastic Basis for the Shape of Borrelia burgdorferi

Detection of Borrelia burgdorferi DNA in Tick Feces Provides Evidence for Organism Shedding During Vector Feeding

Sequence Variation in the Outer-Surface-Protein Genes of Borrelia burgdorferi
by Diane A. Caporale and Thomas D. Kocher

50 Free Published articles
  1. Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection.
  2. Serum antibodies to whole-cell and recombinant antigens of Borrelia burgdorferi in cottontail rabbits.
  3. Adaptive and innate immune responsiveness to Borrelia burgdorferi sensu lato in exposed asymptomatic children and children with previous clinical Lyme borreliosis.
  4. ELISA-based measurement of antibody responses and PCR-based detection profiles can distinguish between active infection and early clearance of Borrelia burgdorferi.
  5. Borrelia burgdorferi enolase is a surface-exposed plasminogen binding protein.
  6. Seroprevalence of Borrelia burgdorferi, Anaplasma phagocytophilum, Ehrlichia canis, and Dirofilaria immitis among dogs in Canada.
  7. Retraction: Detection and differentiation of Borrelia burgdorferi sensu lato in ticks collected from sheep and cattle in China.
  8. Anaplasmataceae and Borrelia burgdorferi sensu lato in the sand lizard Lacerta agilis and co-infection of these bacteria in hosted Ixodes ricinus ticks.
  9. A Case of Atrophoderma of Pasini and Pierini Associated with Borrelia burgdorferi Infection Successfully Treated with Oral Doxycycline.
  10. NMR structure of an acyl-carrier protein from Borrelia burgdorferi.
  11. Biodiversity of Borrelia burgdorferi strains in tissues of Lyme disease patients.
  12. Identification of membrane associated drug targets in Borrelia burgdorferi ZS7- subtractive genomics approach.
  13. Evaluation of in-vitro antibiotic susceptibility of different morphological forms of Borrelia burgdorferi.
  14. Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle.
  15. Analysis of Borrelia burgdorferi Surface Proteins as Determinants in Establishing Host Cell Interactions.
  16. Introduced Siberian chipmunks (Tamias sibiricus barberi) harbor more-diverse Borrelia burgdorferi sensu lato genospecies than native bank voles (Myodes glareolus).
  17. Analysis of the HD-GYP domain cyclic dimeric GMP phosphodiesterase reveals a role in motility and the enzootic life cycle of Borrelia burgdorferi.
  18. Oligopeptide permease A5 modulates vertebrate host-specific adaptation of Borrelia burgdorferi.
  19. The hybrid histidine kinase Hk1 is part of a two-component system that is essential for survival of Borrelia burgdorferi in feeding Ixodes scapularis ticks.
  20. The Borrelia burgdorferi integrin ligand P66 affects gene expression by human cells in culture.
  21. Nitrosative damage to free and zinc-bound cysteine thiols underlies nitric oxide toxicity in wild-type Borrelia burgdorferi.
  22. Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation.
  23. CheY3 of Borrelia burgdorferi is the key response regulator essential for chemotaxis and forms a long-lived phosphorylated intermediate.
  24. Detection and differentiation of Borrelia burgdorferi sensu lato in ticks collected from sheep and cattle in China. * BMC Vet Res. 2011 Apr 29;7:17. Retraction in: BMC Vet Res. 2011;7:56.
  25. Disulfide-mediated oligomer formation in Borrelia burgdorferi outer surface protein C, a critical virulence factor and potential Lyme disease vaccine candidate.
  26. Correlation of Borrelia burgdorferi sensu lato prevalence in questing Ixodes ricinus ticks with specific abiotic traits in the western palearctic.
  27. A novel gene inactivation system reveals altered periplasmic flagellar orientation in a Borrelia burgdorferi fliL mutant.
  28. Investigation of genotypes of Borrelia burgdorferi in Ixodes scapularis ticks collected during surveillance in Canada.
  29. Anti-Borrelia burgdorferi antibody profile in post-Lyme disease syndrome.
  30. Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance.
  31. Differences in prevalence of Borrelia burgdorferi and Anaplasma spp. infection among host-seeking Dermacentor occidentalis, Ixodes pacificus, and Ornithodoros coriaceus ticks in northwestern California.
  32. Analysis of the Borrelia burgdorferi cyclic-di-GMP-binding protein PlzA reveals a role in motility and virulence.
  33. BosR (BB0647) controls the RpoN-RpoS regulatory pathway and virulence expression in Borrelia burgdorferi by a novel DNA-binding mechanism.
  34. Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta.
  35. The OspE-related proteins inhibit complement deposition and enhance serum resistance of Borrelia burgdorferi, the lyme disease spirochete.
  36. Diverse Borrelia burgdorferi strains in a bird-tick cryptic cycle.
  37. Patterns and regulation of ribosomal RNA transcription in Borrelia burgdorferi.
  38. Relationship between immunity to Borrelia burgdorferi outer-surface protein A (OspA) and Lyme arthritis.
  39. Whole genome sequence of an unusual Borrelia burgdorferi sensu lato isolate.
  40. Outer surface protein C is a dissemination-facilitating factor of Borrelia burgdorferi during mammalian infection.
  41. Defining the plasmid-borne restriction-modification systems of the Lyme disease spirochete Borrelia burgdorferi.
  42. Genetic diversity of Borrelia burgdorferi and detection of B. bissettii-like DNA in serum of north-coastal California residents.
  43. Inactivation of bb0184, which encodes carbon storage regulator A, represses the infectivity of Borrelia burgdorferi.
  44. BB0844, an RpoS-regulated protein, is dispensable for Borrelia burgdorferi infectivity and maintenance in the mouse-tick infectious cycle.
  45. Invasion of eukaryotic cells by Borrelia burgdorferi requires β(1) integrins and Src kinase activity.
  46. High-throughput plasmid content analysis of Borrelia burgdorferi B31 by using Luminex multiplex technology.
  47. Distribution of Borrelia burgdorferi sensu lato in China.
  48. CsrA modulates levels of lipoproteins and key regulators of gene expression critical for pathogenic mechanisms of Borrelia burgdorferi.
  49. Proteome analysis of Borrelia burgdorferi response to environmental change.
  50. Borrelia burgdorferi sensu lato in Ixodes ricinus ticks collected from migratory birds in Southern Norway. 

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