Chronic Lymphocytic Leukemia - CLL Lecture Notes and Publications

Chronic Lymphocytic Leukemia - mechanisms of disease
by Nicholas Chiorazzi, M.D., Kanti R. Rai, M.B., B.S., and Manlio Ferrarini, M.D
http://cll.ucsd.edu/biorepository_links/CLL%20ChiorazziRai.pdf

Leukemic Meningitis in Chronic Lymphocytic Leukemia: A Rare Condition Responding to Intrathecal Methotrexate
by Natacha Esber, M.D., Thomas Schulz, M.D
http://archie.kumc.edu/

Gene Expression Profile in B-cell Chronic Lymphocytic Leukemia
by Dohner, Hartnut. Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia.
http://www.wsc.edu/

Molecular Pathophysiology of CLL: Lessons Learned from the Search for Biomarkers of Prognosis
by Lynne V. Abruzzo, M.D., Ph.D
Abruzzo_Molecular_Path_of_CLL.pdf

Too Many B Cells: Chronic Lymphocytic Leukemia and the Role of Flow Cytometry
by Debby R. Walser-Kuntz
http://sciencecases.lib.buffalo.edu/cs/files/flow_cytometry.pdf

Colon and Rectum Chronic Lymphocytic Leukemia
http://ucr.utah.edu/pdf/Leukemia_CLL.pdf

Featured Cases: Chronic Lymphocytic Leukemia (CLL)
by Louis Diehl, MD,
Transcript.pdf

Antibody therapy for chronic lymphocytic leukemia: a promising new modality
by Thomas S. Lin, MD, PhD, Mollie Moran, RNP, Margaret Lucas, PA, Sharon Waymer, LPN, Sara Jefferson, MS, Diane B. Fischer, RN, MS, Michael R. Grever, MD, John C. Byrd, MD
Williams/cllantibodyrx.pdf

Chronic Lymphocytic Leukemia (CLL): First-Line Treatment
FirstLine Treatment


Free 50 Published articles

1. The Aurora A and B kinases are upregulated in bone marrow-derived chronic lymphocytic leukemia cells and represent potential therapeutic targets.
2. IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia.
3. Role of ofatumumab in treatment of chronic lymphocytic leukemia.
4. Composite Hodgkin lymphoma and chronic lymphocytic leukemia: A rare case.
5. Post-GWAS functional characterization of susceptibility variants for chronic lymphocytic leukemia.
6. ATM and chronic lymphocytic leukemia: mutations, and not only deletions, matter.
7. NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL.
8. Physical contact with endothelial cells through β1- and β2- integrins rescues chronic lymphocytic leukemia from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile on leukemic cells.
9. Development of High-Grade B-Cell Lymphoma Concurrent with T-Cell Chronic Lymphocytic Leukemia in a Dog.
10. A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia.
11. Enhancement of fludarabine sensitivity by all-trans retinoic acid in chronic lymphocytic leukemia cells.
12. Targeted treatment for chronic lymphocytic leukemia.
13. The treatment of relapsed refractory chronic lymphocytic leukemia.
14. Using the biology of chronic lymphocytic leukemia to choose treatment.
15. Nurture versus nature: the microenvironment in chronic lymphocytic leukemia.
16. Hematopoietic stem cell allografting for chronic lymphocytic leukemia: a focus on reduced-intensity conditioning regimens.
17. Immunomodulatory drugs and active immunotherapy for chronic lymphocytic leukemia.
18. Treatment of relapsed or refractory chronic lymphocytic leukemia.
19. Front-line therapy for chronic lymphocytic leukemia.
20. Clinical and laboratory prognostic indicators in chronic lymphocytic leukemia.
21. Chronic lymphocytic leukemia: new choices for an old condition.
22. Systematic review of purine analogue treatment for chronic lymphocytic leukemia: lessons for future trials.
23. Evaluation of chronic lymphocytic leukemia by oligonucleotide-based microarray analysis uncovers novel aberrations not detected by FISH or cytogenetic analysis.
24. Th17 and non-Th17 IL-17-expressing cells in chronic lymphocytic leukemia: delineation, distribution, and clinical relevance.
25. AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell -based microenvironment: preclinical evidence for its association with chronic lymphocytic leukemia treatments.
26. Membrane microdomain sphingolipids are required for anti-CD20-induced death of chronic lymphocytic leukemia B cells.
27. Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.
28. Phosphoinositide 3'-kinase delta: turning off BCR signaling in Chronic Lymphocytic Leukemia..
29. Analysis of CD38 and ZAP70 mRNA expression among cytogenetic subgroups of Iranian chronic-lymphocytic-leukemia patients.
30. Differentiation of chronic lymphocytic leukemia B cells into immunoglobulin secreting cells decreases LEF-1 expression.
31. "Surgical" abdomen in a patient with chronic lymphocytic leukemia: a case of acquired angioedema.
32. Concurrent nephrotic syndrome and acute renal failure caused by chronic lymphocytic leukemia (CLL): a case report and literature review.
33. ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression.
34. CD69 is independently prognostic in chronic lymphocytic leukemia: a comprehensive clinical and biological profiling study.
35. Sorafenib-Induced Apoptosis of Chronic Lymphocytic Leukemia Cells Is Associated with Downregulation of RAF and Myeloid Cell Leukemia Sequence 1 (Mcl-1).
36. Chronic lymphocytic leukemia--genomics lead the way.
37. Zosteriform B-cell chronic lymphocytic leukemia infiltration.
38. Leukemia cutis in B-cell chronic lymphocytic leukemia presenting as an episodic papulovesicular eruption.
39. Partial versus Productive Immunoglobulin Heavy Locus Rearrangements in Chronic Lymphocytic Leukemia: Implications for B-Cell Receptor Stereotypy.
40. Intra-clonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells.
41. Persisting right-sided chylothorax in a patient with chronic lymphocytic leukemia: a case report.
42. Torque teno virus 10 isolated by genome amplification techniques from a patient with concomitant chronic lymphocytic leukemia and polycythemia vera.
43. Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes.
44. ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele.
45. Cytogenetic characteristics of B cell chronic lymphocytic leukemia in 275 Chinese patients by fluorescence in situ hybridization: a multicenter study.
46. A rare case of B-cell chronic lymphocytic leukemia with t(2;14)(p13;q32), +X, +11, +12, +13,+der(1p) karyotype.
47. Relevance of stereotyped B-cell receptors in the context of the molecular, cytogenetic and clinical features of chronic lymphocytic leukemia.
48. Differential bone marrow homing capacity of VLA-4 and CD38 high expressing chronic lymphocytic leukemia cells.
49. Therapy-Related Myeloid Neoplasms in Chronic Lymphocytic Leukemia and Waldenstrom's Macroglobulinemia.
50. Increased metastasis of malignant fibrous histiocytoma in patients with chronic lymphocytic leukemia and non-hodgkin lymphoma.